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Shire Licenses CNS Drug

Heptares eligible to receive as much as $190 million plus royalties

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By: Tim Wright

Editor-in-Chief, Contract Pharma

Shire PLC has exercised its exclusive option to license a novel adenosine A2A antagonist discovered by Heptares Therapeutics. Adenosine A2A is a G-protein coupled receptor (GPCR) in preclinical development for the treatment of CNS disorders. Heptares will receive an upfront option grant and exercise payments and is eligible to receive future development and commercial milestone payments of as much as $190 million, plus royalties on sales. Further terms were not disclosed. Jeff Jonas, senior vi...

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